HuagongsheHuagongshe Chemistry Print Report · For research reference only
Quinoline → HCID 70362477, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Quinoline | HCID 7047 | — |
| Reactant | AG-777/36181001 | HCID 808056 | — |
| Catalyst | Lindlars catalyst | HCID 131709914 | — |
| Solvent | Tetrahydrofuran | HCID 8028 | — |
| Product | HCID 70362477 | HCID 70362477 | — |
Reaction Steps
The title compound was prepared from the title product (15 g, 57.4 mmol) of Example 153 by hydrogenation using Lindlar catalyst (2.25 g) and quinoline (0.79 g, 6.09 mmol) in THF (150 ml). The reaction mixture was hydrogenated at 5 psi and 0° to obtain a quantitative yield of the cis product.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04822775 |
| Source dataset | uspto-grants-1989_04 |
| ORD ID | ord-5a04fa5baaf54185b36840063ae1ab6f |
| Source note | uspto-grants-1989_04 |