HuagongsheHuagongshe Chemistry Print Report · For research reference only
Methanol → 6-Methoxy-5-(pentafluoroethyl)naphthalene-1-carboxylic acid
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Methanol | HCID 887 | — |
| Reactant | Potassium Hydroxide | HCID 14797 | — |
| Reactant | 6-Methoxy-5-(pentafluoroethyl)naphthalene-1-carbonitrile | HCID 13959075 | — |
| Product | 6-Methoxy-5-(pentafluoroethyl)naphthalene-1-carboxylic acid | HCID 13959076 | — |
Reaction Steps
The crude 6-MPCN product of Example I was dissolved in 135 ml of methanol and 40 ml of a potassium hydroxide solution (4.5 g of KOH in 40 ml of water) and heated to 125° C./70 psi for seven hours. The reaction mixture was then worked up and acidified to yield 6.6 g of 6-methoxy-5-pentafluoroethyl-1-naphthoic acid.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04822904 |
| Source dataset | uspto-grants-1989_04 |
| ORD ID | ord-e068ca684b12495ea1a22f603bb92f37 |
| Source note | uspto-grants-1989_04 |