HuagongsheHuagongshe Chemistry Print Report · For research reference only
Azobisisobutyronitrile → Methyl 2-[2-(bromomethyl)phenyl]-3-methoxyprop-2-enoate
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Azobisisobutyronitrile | HCID 6547 | — |
| Reactant | Succinimide | HCID 11439 | — |
| Reactant | N-bromobutanimide | HCID 67184 | — |
| Reactant | Methyl 3-methoxy-2-o-tolylacrylate | HCID 435882 | — |
| Solvent | Carbon Tetrachloride | HCID 5943 | — |
| Product | Methyl 2-[2-(bromomethyl)phenyl]-3-methoxyprop-2-enoate | HCID 53395349 | — |
Reaction Steps
20.6 g of the methyl α-(2-methylphenyl)-β-methoxyacrylate obtained by Method A, 17.65 g of N-bromosuccinimide, 0.2 g of azodiisobutyronitrile and 150 ml of CCl4 are slowly heated to 90° C. This temperature is maintained until all the succinimide is floating on the solvent. Filtration is followed by concentrating, the remaining oil is dissolved in about 5 ml of acetone, and n-hexane is added to bring about crystallization. This gives 27.5 g of colorless crystals of mp 86°-87° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04822908 |
| Source dataset | uspto-grants-1989_04 |
| ORD ID | ord-9b8c870e7d334ddbab992dc982eb8816 |
| Source note | uspto-grants-1989_04 |