(1-Chloroethyl)benzene → 1-(3-Vinylphenyl)-1-phenylethane

Participants

Reaction Steps

(1-Chloroethyl)benzene (formula VI) is subjected to coupling reaction with a Grignard reagent of 3-vinylphenylmagnesium bromide (formula VII) in the presence of a catalyst of nickel chloride (II)-diphosphine complex, to obtain 1-(3-vinylphenyl)-1-phenylethane. The reaction is carried out in a nitrogen atmosphere under atmospheric pressure at a temperature of 0° to 80° C. The ratio of (VI)/(VII) may be in the range of about 1.0 to 1.5. ##STR9##

Provenance & Evidence