HuagongsheHuagongshe Chemistry Print Report · For research reference only
Acetate → HCID 54340402, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Acetate | HCID 175 | — |
| Reactant | Sodium Acetate | HCID 517045 | — |
| Reactant | Ethyl alpha-oxobenzenebutanoate | HCID 562087 | — |
| Reactant | HCID 54079930 | HCID 54079930 | — |
| Catalyst | Nickel | HCID 935 | — |
| Solvent | Ethanol | HCID 702 | — |
| Product | HCID 54340402 | HCID 54340402 | 33.3% |
Reaction Steps
L-Alanyl-N-(5,6-dimethoxyindan-1-yl)glycine tert-butyl ester (4.0 g) is dissolved in 80 ml of ethanol, and 0.77 g of sodium acetate, 4.0 g of acetate acid, 4.0 g of ethyl 2-oxo-4-phenyl-butyrate, 12 g of molecular sieve 3A and 6.0 g of Raney nickel are added. Thereafter, the reaction and treatment are carried out as in Example 2 to give 2.0 g of N-(1-ethoxycarbonyl-3-phenylpropyl)-L-alanyl-N-(5,6-dimethoxyindan-1-yl)glycine tert-butyl ester as slightly yellow oil.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04822818 |
| Source dataset | uspto-grants-1989_04 |
| ORD ID | ord-9d7765672b1c4874a7e04a0a6b83c3a5 |
| Source note | uspto-grants-1989_04 |