3-Chlorobenzaldehyde → 2-(m-Chlorophenyl)-5-ethyl-1,3-oxazolidine

HRID 621374Notes

Reaction equation

HRID 621374 reaction equation
[Cl:1][C:2]1[CH:3]=[C:4]([CH:7]=[CH:8][CH:9]=1)[CH:5]=[O:6].[NH2:10][CH2:11][CH:12](O)[CH2:13][CH3:14]>>[Cl:1][C:2]1[CH:3]=[C:4]([CH:5]2[NH:10][CH2:11][CH:12]([CH2:13][CH3:14])[O:6]2)[CH:7]=[CH:8][CH:9]=1

Participants

3

Reactant 2

HCID 114773-ChlorobenzaldehydeHCID 261071-Amino-2-butanol

Product 1

HCID 156146152-(m-Chlorophenyl)-5-ethyl-1,3-oxazolidine

Procedure

Twenty-five grams of m-chlorobenzaldehyde was combined with 15.8 g of 1-amino-2-butanol and heated on the rotary evaporator for 1 hour to remove water. The yield was 37.9 g, nD30 1.5741.

Workup

  1. temperatureheated on the rotary evaporator for 1 hour
  2. customto remove water

Sources & evidence

ORD record
ord-ee5383886a9845c4adddfc3ff6baf413
Source dataset
uspto-grants-1989_04
Patent number
US04824468

Reaction notes

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