HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 621386Generated: October 31, 2026
Formic Acid → methyl N-(decahydro-1-naphthalenyl)-N-formylglycine
https://huagongshe.com/reaction/621386
Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | Formic Acid | HCID 284 | — |
| Reactant | Acetic Anhydride | HCID 7918 | — |
| Reactant | methyl N-(decahydro-1-naphthalenyl)glycine | HCID 70377605 | — |
| Product | methyl N-(decahydro-1-naphthalenyl)-N-formylglycine | HCID 86742951 | 89.4% |
Reaction Steps
150 Parts of methyl N-(decahydro-1-naphthalenyl)glycine were added dropwise to 372 parts of formic acid while cooling (5° C.). Upon complete addition, 110 parts of acetic acid anhydride were added. The reaction mixture was stirred for 17 hours at room temperature. The whole was distilled in vacuo, yielding 142.8 parts (89.4%) of methyl N-(decahydro-1-naphthalenyl)-N-formylglycine as a residue (intermediate 6).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
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| Patent number | US04824472 |
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| Source dataset | uspto-grants-1989_04 |
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| ORD ID | ord-3869677ef79f410b80d55d0f995af785 |
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| Source note | uspto-grants-1989_04 |
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