HuagongsheHuagongshe Chemistry Print Report · For research reference only
Ethanol → HCID 178456465, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Ethanol | HCID 702 | — |
| Reactant | Methyl isothiocyanate | HCID 11167 | — |
| Reactant | HCID 14986830 | HCID 14986830 | — |
| Solvent | Dimethylformamide | HCID 6228 | — |
| Product | HCID 178456465 | HCID 178456465 | 70% |
Reaction Steps
A solution of 1-benzyl-6-hydrazino-3-propyluracil (2.0 g, 7.3 mM) and methyl isothiocyanate (1.5 ml, 22 mM) in DMF (20 ml) was stirred at 120° C. for 20 hours. Ethanol (20 ml) was added to the solution, which was cooled to give crystals. Recrystallization from DMF/ethanol gave colorless needles (1.6 g, 70%), m.p. 307°-310° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04824848 |
| Source dataset | uspto-grants-1989_04 |
| ORD ID | ord-d053f8bf0c3b48fba1305003709f9a13 |
| Source note | uspto-grants-1989_04 |