Methanol → HCID 178456471, compound

Participants

Reaction Steps

A solution of 6-hydrazino-1-(4-pyridylmethyl)-3-propyluracil (1.5 g, 5.7 mM) and methyl isothiocyanate (1.55 ml, 23 mM) in DMF (15 ml) was heated at 90° C. for 14 hours and then at 110° C. for 14 hours. To the reaction solution was added 50% methanol (10 ml) and the mixture was cooled to give crystals. Recrystallization from DMF/ethanol/water afforded colorless needles (1.02 g, 57%), m.p. >300° C.

Provenance & Evidence