Methanol → HCID 178456472, compound

Participants

Reaction Steps

A solution of 6-hydrazino-1-phenethyl-3-propyluracil (1.5 g, 5.2 mM) and methyl isothiocyanate (1.1 ml, 16 mM) in DMF (15 ml) was stirred at 60° C. for 2 hours and then at 120° C. for 15 hours. To the solution was added 50% methanol (10 ml) and the mixture was cooled to give crystals. Recrystallization from DMF/methanol afforded colorless crystals (0.7 g, 41%), m.p. 256°-258° C.

Provenance & Evidence