Methanol → HCID 178456473, compound

Participants

Reaction Steps

A solution of 1-(2-benzyloxyethyl)-6-hydrazino-3-propyluracil (2.0 g, 6.3 mM) and methyl isothiocyanate (1.2 ml, 18 mM) in DMF (20 ml) was stirred at 60° C. for 1 hour and then at 100° C. for 20 hours. To the solution was added 50% methanol (10 ml) and the mixture was cooled to give crystals. Recrystallization from DMF/methanol afforded colorless prisms (1.39 g, 62%), m.p. 224°-226° C.

Provenance & Evidence