HuagongsheHuagongshe Chemistry Print Report · For research reference only
Diethylene Glycol Monoethyl Ether → HCID 21243293, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Diethylene Glycol Monoethyl Ether | HCID 8146 | — |
| Reactant | Sodium Hydroxide | HCID 14798 | — |
| Reactant | 2-[4-(5-Carbamoyl-3-indolyl)butyl]-1,2,3,4-tetrahydrobenzofuro[2,3-c]pyridine | HCID 21243285 | — |
| Solvent | Water | HCID 962 | — |
| Product | HCID 21243293 | HCID 21243293 | — |
Reaction Steps
A mixture of 38.7 g of 2-[4-(5-carbamoyl-3-indolyl)butyl]-1,2,3,4-tetrahydrobenzofuro[2,3-c]pyridine, 27.1 g of NaOH, 525 ml of water and 450 ml of diethylene glycol monoethyl ether is boiled, with stirring, for 16 hours. The mixture is cooled, the usual working up followed by acidification is carried out, and 2-[4-(5-carboxy-3-indolyl)butyl]-1,2,3,4-tetrahydrobenzofuro[2,3-c]pyridine is obtained.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04824852 |
| Source dataset | uspto-grants-1989_04 |
| ORD ID | ord-e757f667ccc444b382d1c12706a7ab0d |
| Source note | uspto-grants-1989_04 |