HCID 15614680, compound → HCID 13653956, compound

Participants

Reaction Steps

A solution of N-benzyl-N-methyl-2-benzyl-3-(3-methoxyphenoxy)propylamine (7.0 g) in ethanol (100 ml) is hydrogenated at room temperature and atmospheric pressure until uptake ceases, using 10% palladium on charcoal (2.0 g) as catalyst. The catalyst is filtered off (Hi-flo) and the solvent removed under reduced pressure to give N-methyl-2-benzyl-3-(3-methoxyphenoxy)propylamine as an oil, which is converted with oxalic acid in ether to N-methyl-2-benzyl-3-(3-methoxyphenoxy)propylamine oxalate, m.p. 127°-129°.

Provenance & Evidence