反应详情

A mixture of 3-amino-2-carbamoyl-4-phenylpyrazole (4.8 g) and ethyl orthoformate (30 ml) is stirred at 100°-110° C. for 13 hours, and thereto is added methanol acetate. The precipitate is separated by filtration, washed with methanol or ethyl acetate, and dried to give the title compound (2.08 g).

1. customThe precipitate is separated by filtration
2. washwashed with methanol or ethyl acetate
3. customdried