Methyl Acetate → HCID 178517942, compound

HRID 621648Notes

Reaction equation

HRID 621648 reaction equation
[NH2:1][C:2]1[N:3]([C:13](=[O:15])[NH2:14])[N:4]=[CH:5][C:6]=1[C:7]1[CH:12]=[CH:11][CH:10]=[CH:9][CH:8]=1.[C:16](OC)(=O)C>C([O-])([O-])OCC>[OH:15][C:13]1[N:3]2[N:4]=[CH:5][C:6]([C:7]3[CH:12]=[CH:11][CH:10]=[CH:9][CH:8]=3)=[C:2]2[N:1]=[CH:16][N:14]=1

Participants

4

Reactant 2

HCID 6584Methyl AcetateHCID 156159363-Amino-2-carbamoyl-4-phenylpyrazole

Product 1

HCID 178517942HCID 178517942, compound

Reagents, catalysts & solvents 1

HCID 53630039EthylorthoformateSolvent

Procedure

A mixture of 3-amino-2-carbamoyl-4-phenylpyrazole (4.8 g) and ethyl orthoformate (30 ml) is stirred at 100°-110° C. for 13 hours, and thereto is added methanol acetate. The precipitate is separated by filtration, washed with methanol or ethyl acetate, and dried to give the title compound (2.08 g).

Workup

  1. customThe precipitate is separated by filtration
  2. washwashed with methanol or ethyl acetate
  3. customdried

Sources & evidence

ORD record
ord-21f859648a004f49b76a4d80906220aa
Source dataset
uspto-grants-1989_04
Patent number
US04824834

Reaction notes

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