Acetic Acid → HCID 178526531, compound

HRID 621651Notes

Reaction equation

HRID 621651 reaction equation
S(=O)(=O)(O)O.[N+:6]([O-:9])(O)=[O:7].C(O)(=O)C.[OH:14][C:15]1[N:20]2[N:21]=[CH:22][C:23]([C:24]3[CH:29]=[CH:28][CH:27]=[CH:26][CH:25]=3)=[C:19]2[N:18]=[CH:17][N:16]=1>O>[OH:14][C:15]1[N:20]2[N:21]=[CH:22][C:23]([C:24]3[CH:29]=[CH:28][C:27]([N+:6]([O-:9])=[O:7])=[CH:26][CH:25]=3)=[C:19]2[N:18]=[CH:17][N:16]=1

Participants

6

Reactant 4

HCID 176Acetic AcidHCID 944Nitric AcidHCID 1118Sulfuric AcidHCID 178517942HCID 178517942, compound

Product 1

HCID 178526531HCID 178526531, compound

Reagents, catalysts & solvents 1

HCID 962WaterSolvent

Procedure

To a mixture of conc. sulfuric acid (0.5 ml), conc. nitric acid (0.5 ml) and acetic acid (2 ml) is addded 4-hydroxy-8-phenylpyrazolo[1,5-a]-1,3,5-triazine (310 mg), and the mixture is stirred at 50°-60° C. After reacting for one hour, to the reaction mixture is added water. The insoluble material is separated by filtration, washed with water and hot methanol and dried to give the title compound (210 mg).

Workup

  1. customThe insoluble material is separated by filtration
  2. washwashed with water and hot methanol
  3. customdried

Sources & evidence

ORD record
ord-8c6c69c94a1d463c93b8a3a1875611ec
Source dataset
uspto-grants-1989_04
Patent number
US04824834

Reaction notes

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