Nitrobenzene → HCID 178515938, compound

HRID 621653Notes

Reaction equation

HRID 621653 reaction equation
[OH:1][C:2]1[N:7]2[N:8]=[CH:9][C:10]([C:11]3[CH:16]=[CH:15][CH:14]=[CH:13][C:12]=3[O:17]C)=[C:6]2[N:5]=[CH:4][N:3]=1.[Cl-].[Al+3].[Cl-].[Cl-].[N+](C1C=CC=CC=1)([O-])=O>>[OH:1][C:2]1[N:7]2[N:8]=[CH:9][C:10]([C:11]3[CH:16]=[CH:15][CH:14]=[CH:13][C:12]=3[OH:17])=[C:6]2[N:5]=[CH:4][N:3]=1

Participants

4

Reactant 3

HCID 7416NitrobenzeneHCID 6451240Aluminum(III) ChlorideHCID 178489325HCID 178489325, compound

Product 1

HCID 178515938HCID 178515938, compoundYield 61.4%

Procedure

A mixture of 4-hydroxy-8-(2-methoxyphenyl)pyrazolo[1,5-a]-1,3,5-triazine (242 mg), aluminum chloride (799 mg) and nitrobenzene (3 ml) is stirred at 80°-90° C. for 5 hours. The reaction mixture is cooled and poured into ice water. The precipitate is separated by filtration, washed with water and dried to give the title compound (140 mg).

Workup

  1. temperatureThe reaction mixture is cooled
  2. customThe precipitate is separated by filtration
  3. washwashed with water
  4. customdried

Sources & evidence

ORD record
ord-d6eed063ce754b91bd49c883b2644664
Source dataset
uspto-grants-1989_04
Patent number
US04824834

Reaction notes

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