Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | Isopropylamine | HCID 6363 | — |
| Reactant | Diethyl acetonedicarboxylate | HCID 66045 | — |
| Product | HCID 73751838 | HCID 73751838 | 36% |
Reaction Steps
Isopropylamine (60 ml, 0.712 mol) was added slowly to diethyl 1,3-acetonedicarboxylate (120 g, 0.5934 mol) with stirring at -18° C. After 24 hours at room temperature, the excess amine and water were removed under rotary evaporation and finally by azeotropic distillation with benzene to give a light yellow oil. It was kugelrohr distilled to give 52 g of light yellow oil as product (30%), nD25 1.4887.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| Patent number | US04824954 |
|---|
| Source dataset | uspto-grants-1989_04 |
|---|
| ORD ID | ord-8f0a5cd80e6b4fa3997f4d7639563f48 |
|---|
| Source note | uspto-grants-1989_04 |
|---|
