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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 621785Generated: October 30, 2026

Bromine → Methyl 4-bromo-3-hydroxy-5-phenyl-2-thiophenecarboxylate

https://huagongshe.com/reaction/621785

Reaction equation

Participants

RoleNameHCIDCharge
ReactantBromineHCID 24408—
ReactantMethyl 3-hydroxy-5-phenyl-2-thiophenecarboxylateHCID 54710750—
ProductMethyl 4-bromo-3-hydroxy-5-phenyl-2-thiophenecarboxylateHCID 5469714860.8%

Reaction Steps

Prepared by the method described in Example 4 from methyl 3-hydroxy-5-phenyl-2-thiophenecarboxylate (5.0 g, 21 mmoles) and bromine (3.4 g, 21 mmoles). Recrystallization from methanol gave the product (4.0 g); mp 85°-87° C.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS04824958
Source datasetuspto-grants-1989_04
ORD IDord-51bfffc1cc3f48bfba7729fb1fa37a5a
Source noteuspto-grants-1989_04