HuagongsheHuagongshe Chemistry Print Report · For research reference only
Dimethylamine → HCID 23037338, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Dimethylamine | HCID 674 | — |
| Reactant | 1,1'-Carbonyldiimidazole | HCID 68263 | — |
| Reactant | 2-(3-Chlorophenyl)-3H-imidazo[4,5-b]pyridine-3-acetic acid | HCID 14390454 | — |
| Solvent | Tetrahydrofuran | HCID 8028 | — |
| Product | HCID 23037338 | HCID 23037338 | — |
Reaction Steps
Under nitrogen bubbling, a mixture of 2-(3-chlorophenyl)-3H-imidazo[4,5-b]pyridine-3acetic acid (4.0 g, 0.0138 mole) and 1,1'-carbonyldiimidazole (2.24 g, 0.0138 mole) in 150 ml of tetrahydrofuran was stirred at room temperature for 4 hrs. A solution of dimethylamine in tetrahydrofuran (42 ml of 0.5M solution) was added, and the reaction mixture was allowed to stir at room temperature for 1/2 hr.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04824951 |
| Source dataset | uspto-grants-1989_04 |
| ORD ID | ord-96809039a2304d959fcddae5a91e0a31 |
| Source note | uspto-grants-1989_04 |