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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 621978Generated: October 29, 2026

2-Methoxyethylamine → HCID 14390337, compound

https://huagongshe.com/reaction/621978

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-MethoxyethylamineHCID 8018—
Reactant1,1'-CarbonyldiimidazoleHCID 68263—
Reactant4-chlorophenyl-3H-imidazo[4,5-b]pyridine-3-acetic acidHCID 14390457—
SolventTetrahydrofuranHCID 8028—
ProductHCID 14390337HCID 14390337—

Reaction Steps

Under nitrogen bubbling, a mixture of 2-(4-chlorophenyl)-3H-imidazo[4,5-b]pyridine-3-acetic acid (4.37 g, 0.015 mole) and 1,1'-carbonyldiimidazole (2.59 g, 0.016 mole) in 150 ml of tetrahydrofuran was stirred at room temperature for 4 hrs. 2-Methoxyethylamine (1.71 g, 0.023 mole) was added and the reaction mixture was allowed to stir at room temperature overnight.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS04824951
Source datasetuspto-grants-1989_04
ORD IDord-9ec2757fd0d844ada3838f8364880cf3
Source noteuspto-grants-1989_04