HCID 131715711, compound → HCID 22839553, compound

Participants

Reaction Steps

A solution of Example 3 (1.2 g) in methanol (50 mls) was hydrogenated over 10% palladium on charcoal (0.2 g) for 17 hours. The catalyst was filtered off, and the filtrate was evaporated to dryness. Crystallisation of the resulting solid from isopropyl alcohol/methanol gave the title compound (0.63 g). M.p. 259°. NMR (DMSOd6) δ 9.9 (2H, Br S, NH2+), 7.2-6.85 (3H, m, aromatic), 4.24 (1H, d of t, 3a-H), 3.8-2.78 (6H, m, 1-H2, 3-H2, 9-H2), 2.27 (1H, m, 9a-H).

Provenance & Evidence