Benzene → HCID 14257095, compound

HRID 622100Notes

Reaction equation

HRID 622100 reaction equation
[C:1]1([C:7]2(O)[C:19]3[CH:18]=[N:17][CH:16]=[N:15][C:14]=3[C:13]3[C:8]2=[CH:9][CH:10]=[CH:11][CH:12]=3)[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=1.C1C=CC=CC=1.S(Cl)([Cl:29])=O>>[Cl:29][C:7]1([C:1]2[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=2)[C:19]2[CH:18]=[N:17][CH:16]=[N:15][C:14]=2[C:13]2[C:8]1=[CH:9][CH:10]=[CH:11][CH:12]=2

Participants

4

Reactant 3

HCID 241BenzeneHCID 24386Thionyl ChlorideHCID 21293480HCID 21293480, compound

Product 1

HCID 14257095HCID 14257095, compound

Procedure

Five grams of 5-phenyl-5H-indeno[1,2-d]pyrimidin-5-ol were stirred at reflux temperature in 25 ml of thionyl chloride and 100 ml of benzene for 5 hours. The solvents were removed by evaporation and the residue was tritrated with benzene and filtered. The solid was crystallized from diethyl ether to provide 3 g of the desired title product, m.p. 119°-120° C.

Workup

  1. customThe solvents were removed by evaporation
  2. filtrationfiltered
  3. customThe solid was crystallized from diethyl ether

Sources & evidence

ORD record
ord-4ea0ad403a534e66926765d978d7eded
Source dataset
uspto-grants-1988_09
Patent number
US04769378

Reaction notes

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