Water → HCID 14097220, compound

HRID 622208Notes

Reaction equation

HRID 622208 reaction equation
Br[C:2]1[CH:6]=[CH:5][S:4][C:3]=1[C:7]([C:10]1[CH:15]=[CH:14][CH:13]=[CH:12][C:11]=1[O:16][CH3:17])=[N:8][OH:9].O.[OH-].[K+]>C(OC(O)C)C>[CH3:17][O:16][C:11]1[CH:12]=[CH:13][CH:14]=[CH:15][C:10]=1[C:7]1[C:3]2[S:4][CH:5]=[CH:6][C:2]=2[O:9][N:8]=1

Participants

5

Reactant 3

HCID 962WaterHCID 14797Potassium HydroxideHCID 86160832HCID 86160832, compound

Product 1

HCID 14097220HCID 14097220, compound

Reagents, catalysts & solvents 1

HCID 101298981-EthoxyethanolSolvent

Procedure

A solution of 12.0 g of (3-bromothien-2-yl) (2-methoxyphenyl)methanone oxime in 220 ml of ethoxyethanol was combined with 15 ml of water containing 4.3 g of potassium hydroxide pellets (85%) and the mixture was stirred at 110° for 10 minutes and thereafter 0.28 g of cuprous chloride was added. Stirring was maintained at this temperature under nitrogen for one hour.

Workup

  1. stirringStirring
  2. temperaturewas maintained at this temperature under nitrogen for one hour

Sources & evidence

ORD record
ord-0d31ae3aadba4c99b9e39531be3543ef
Source dataset
uspto-grants-1988_09
Patent number
US04769472

Reaction notes

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