Sulfate Ion → 2,3,4,5-Tetrafluorobenzoic acid

Participants

Reaction Conditions

Reaction Steps

In an autoclave having an inner volume of 1 liter, 150 g (0.630 mole) of 3,4,5,6-tetrafluorophthalic acid containing no sulfate ion, 29.1 g (0.220 mole) of ammonium sulfate, and 500 g of water were placed and heated and stirred for reaction at 160° C. for 21 hours [pH 1.74 at 30° C. at the time of charging]. After completion of the reaction, the reaction suspension was cooled to room temperature, filtered, washed with water, and then dried, to produce 2,3,4,5-tetrafluorobenzoic acid. Calculation from the amount obtained by filtration and the amount obtained by extraction as in Example 1 reveals that this example produced 2,3,4,5-tetrafluorobenzoic acid in a yield of 85.8 mole %.

Provenance & Evidence