反应详情

2-Chloro-4-fluorophenol (83.4 g) was added to a solution of sodum hydroxide (27.7 g) in water (450 ml), and methyl chloroformate (69.2 g) was dropwise added thereto at a temperature below 10° C. Precipitated crystals were collected by filtration and washed with water to give methyl (2-chloro-4-fluorophenyl)formate (134.8 g). M.P., 69°-71° C.

1. additionwas dropwise added
2. customat a temperature below 10° C
3. customPrecipitated crystals
4. filtrationwere collected by filtration
5. washwashed with water