Nitric Acid → HCID 14305141, compound

HRID 622307Notes

Reaction equation

HRID 622307 reaction equation
N([O-])=O.[Na+].[N+]([O-])(O)=O.[CH3:9][C:10]1[CH:15]=[CH:14][C:13]([CH:16]([N:20]2[C:24]([C:25]([O:27][CH3:28])=[O:26])=[CH:23][N:22]=[C:21]2S)[CH2:17][CH2:18][CH3:19])=[CH:12][CH:11]=1>O>[CH3:9][C:10]1[CH:15]=[CH:14][C:13]([CH:16]([N:20]2[C:24]([C:25]([O:27][CH3:28])=[O:26])=[CH:23][N:22]=[CH:21]2)[CH2:17][CH2:18][CH3:19])=[CH:12][CH:11]=1

Participants

5

Reactant 3

HCID 944Nitric AcidHCID 23668193Sodium NitriteHCID 178440831HCID 178440831, compound

Product 1

HCID 14305141HCID 14305141, compoundYield 86%

Reagents, catalysts & solvents 1

HCID 962WaterSolvent

Procedure

0.07 Parts of sodium nitrite and 0.6 parts of nitric acid were solved in 2 parts of deionisized water. 1.0 Part of methyl 1-[1-(4-methylphenyl)butyl]-2-mercapto-1H-imidazole-5-carboxylate was added portionwise at a temperature between 25° C. and 30° C. The precipitate was isolated, yielding 0.94 parts (86% ) of methyl 1-[1-(4-methylphenyl)butyl]-1H-imidazole-5-carboxylate mononitriate. This colourless salt has a melting point of 141°-143° C. (compound 1.15).

Workup

  1. customThe precipitate was isolated

Sources & evidence

ORD record
ord-7826e7ff4a4340a58ddcb59b18506122
Source dataset
uspto-grants-1988_09
Patent number
US04770689

Reaction notes

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