HCID 14460512, compound → 3-(3-Cyclopropyl-1,2,4-oxadiazol-5-yl)-4,5-dihydro-4-methyl5-oxo-6-bromo-imidazo(1,5-a)quinazoline

HRID 622359Notes

Reaction equation

HRID 622359 reaction equation
[CH3:1][N:2]1[C:11](=[O:12])[C:10]2[C:5](=[CH:6][CH:7]=[CH:8][C:9]=2[Br:13])[NH:4][C:3]1=O.[CH:15]1([C:18]2[N:22]=[C:21]([CH2:23][N+:24]#[C-:25])[O:20][N:19]=2)[CH2:17][CH2:16]1>>[CH:15]1([C:18]2[N:22]=[C:21]([C:23]3[N:24]=[CH:25][N:4]4[C:5]5[C:10](=[C:9]([Br:13])[CH:8]=[CH:7][CH:6]=5)[C:11](=[O:12])[N:2]([CH3:1])[C:3]=34)[O:20][N:19]=2)[CH2:17][CH2:16]1

Participants

3

Reactant 2

HCID 14460512HCID 14460512, compoundHCID 229129243-Cyclopropyl-5-(isocyanomethyl)-1,2,4-oxadiazole

Product 1

HCID 212876803-(3-Cyclopropyl-1,2,4-oxadiazol-5-yl)-4,5-dihydro-4-methyl5-oxo-6-bromo-imidazo(1,5-a)quinazoline

Procedure

M.p. 246°-247° C. by reaction between 3-methyl-5-bromo-1,2,3,4-tetrahydro-2,4-dioxo-quinazoline and 3-cyclopropyl-5-isocyanomethyl-1,2,4-oxadiazole.

Sources & evidence

ORD record
ord-eb55c273e1a0426297ccb76d1a780dd1
Source dataset
uspto-grants-1988_09
Patent number
US04771051

Reaction notes

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