2-Aminothiophenol → HCID 14234695, compound

Participants

Reaction Steps

In the same manner as in Reference Example 9, methyl 2-bromo-3-methylvalerate (1:1 diastereomer mixture) and 2-aminothiophenol were allowed to react followed by ring closure reaction, to give 2-(1-methylpropyl)-2H-1,4-benzothiazin-3(4H)-one (1:1 diastereomer mixture) as colorless prisms. mp 99°-100° C. (recrystallized from ethanol). Yield 72.6%.

Provenance & Evidence