Magnesium monoxide → 1404-26-8

Participants

Reaction Steps

4.8 g of Polymyxin B sulfate (purchased from Sigma Chemicl Co.; 8000 units/mg) were dissolved in 600 ml water and 25 g of Fiber A were added therein, followed by 5 hours shaking. Then 1.5 g of magnesium oxide were added thereto, followed by 12 hours shaking at room temperature. Thereafter, the fiber was taken out from the mother liquor, packed in a column and washed with 4800 ml of 0.1N-hydrochloric acid. Polymyxin B-fixed fiber (Fiber D) was obtained. The amount of fixed Polymyxin on Fiber D was determined by the same method of Example 1. It was 39 mg/g.

Provenance & Evidence