HCID 13772782, compound → HCID 13772781, compound

HRID 622500Notes

Reaction equation

HRID 622500 reaction equation
[CH2:1]([NH:3][CH2:4][C:5]1[S:6][CH:7]=[C:8]([C:10]2[C:19]([F:20])=[C:18]3[C:13]([C:14](=[O:27])[C:15]([C:24]([OH:26])=[O:25])=[CH:16][N:17]3[CH2:21][CH2:22][F:23])=[CH:12][C:11]=2[F:28])[N:9]=1)C.NCC1SC=C(C2C(F)=CC3C(=O)C(C(O)=O)=CN4C(C)COC=2C=34)N=1>>[F:28][C:11]1[CH:12]=[C:13]2[C:18](=[C:19]([F:20])[C:10]=1[C:8]1[N:9]=[C:5]([CH2:4][NH:3][CH3:1])[S:6][CH:7]=1)[N:17]([CH2:21][CH2:22][F:23])[CH:16]=[C:15]([C:24]([OH:26])=[O:25])[C:14]2=[O:27]

Participants

3

Reactant 2

HCID 13772782HCID 13772782, compoundHCID 13772842HCID 13772842, compound

Product 1

HCID 13772781HCID 13772781, compound

Procedure

7-[2-[(ethylamino)methyl]-4-thiazolyl]-6,8-difluoro-1-(2-fluoroethyl)-1,4-dihydro-4-oxo-3-quinolinecarboxylic acid, mp 197°-201° C. (35e), and 10-[2-(aminomethyl)-4-thiazolyl]-9-fluoro-2,3-dihydro-3-methyl-7-oxo-7H-pyrido[1,2,3-de]-1,4-benzoxazine-6-carboxylic acid, mp 229°-231° C. (35f).

Sources & evidence

ORD record
ord-01618c8b4ced46b0934c88a544ef5959
Source dataset
uspto-grants-1988_09
Patent number
US04771054

Reaction notes

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