HuagongsheHuagongshe Chemistry Print Report · For research reference only
Potassium tert-butoxide → Ethyl 8-chloro-1-cyclopropyl-6,7-difluoro-4-oxo-1,4-dihydroquinoline-3-carboxylate
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Potassium tert-butoxide | HCID 23665647 | — |
| Reactant | HCID 178471875 | HCID 178471875 | — |
| Solvent | tert-Butanol | HCID 6386 | — |
| Product | Ethyl 8-chloro-1-cyclopropyl-6,7-difluoro-4-oxo-1,4-dihydroquinoline-3-carboxylate | HCID 13579166 | — |
Reaction Steps
To a solution of ethyl 2-(3-chloro-2,4,5-trifluorobenzoyl)-3-cyclopropylaminoacrylate in 40 ml of dry t-butanol was added a slurry of 1.20 g (10.7 mmol) of potassium t-butoxide in 20 ml of dry t-butanol.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04771054 |
| Source dataset | uspto-grants-1988_09 |
| ORD ID | ord-de36f5dc6c244ac5a3a675b34741df37 |
| Source note | uspto-grants-1988_09 |