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HRID622586

反应详情

EQUATION

反应方程式

HRID 622586 的结构方程式

REACTANTS

反应物

2
结构：CCOC(=O)CC
HCID7749

Ethyl propionate

C5H10O2

结构：[N-]=[N+]=N[C@@H]1NC(=O)[C@H]1NC(c1ccccc1)(c1ccccc1)c1ccccc1
HCID53771026

未命名化合物

PRODUCTS

生成物

1
结构：CCOC(=O)c1cn([C@@H]2NC(=O)[C@H]2NC(c2ccccc2)(c2ccccc2)c2ccccc2)nn1
HCID70415279

未命名化合物

收率 51.4%

AUXILIARIES

试剂、催化剂与溶剂

1
结构：Cc1ccccc1
溶剂HCID1140

Toluene

C7H8

PROCEDURE

实验过程

To a solution of 2.0 g of (3S,4S)-4-azido-3-tritylamino-2-azetidinone in 40 ml of toluene is added 1.33 g of ethyl propionate, and the mixture is refluxed for one hour and then cooled. The resulting crystalline is collected by filtration and dried to give 1.3 g of (3S,4S)-4-[4-(ethoxycarbonyl)-1,2,3-triazol-1-yl]-3-tritylamino-2-azetidinone.

WORKUP

后处理

  1. temperaturethe mixture is refluxed for one hour
  2. temperaturecooled
  3. filtrationThe resulting crystalline is collected by filtration
  4. customdried