HuagongsheHuagongshe Chemistry Print Report · For research reference only
N-bromobutanimide → HCID 136096006, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | N-bromobutanimide | HCID 67184 | — |
| Reactant | 2-Amino-9-[(thiophen-2-yl)methyl]-3,9-dihydro-6H-purin-6-one | HCID 136093122 | — |
| Solvent | Water | HCID 962 | — |
| Solvent | Dimethylformamide | HCID 6228 | — |
| Product | HCID 136096006 | HCID 136096006 | — |
Reaction Conditions
| Temperature | 0 °C |
|---|
Reaction Steps
N-Bromosuccinimide (2.82 g; 15.7 mmol) was added to a cold (0° C. suspension of 9-(2-thenyl)guanine (3.5 g; 14.1 mmol) in DMF (100 ml) and the mixture was stirred for 30 minutes at 0° C. and then at room temperature for 24 hours. The reaction mixture was then diluted with 75 ml of water and filtered. Recrystallization of the product from DMF gave the analytical sample, yield 3.1 g; mp 294°-295° C. (dec).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04772606 |
| Source dataset | uspto-grants-1988_09 |
| ORD ID | ord-e3200e0d19804d94acc64481c521db63 |
| Source note | uspto-grants-1988_09 |