Chlorosulfonic acid → HCID 15269533, compound

HRID 622685Notes

Reaction equation

HRID 622685 reaction equation
[Cl:1][C:2]1[CH:11]=[C:10]2[C:5]([C:6](=[O:13])[CH:7]=[CH:8][N:9]2[CH3:12])=[CH:4][CH:3]=1.[Cl:14][S:15](O)(=[O:17])=[O:16]>>[Cl:1][C:2]1[CH:11]=[C:10]2[C:5]([C:6](=[O:13])[C:7]([S:15]([Cl:14])(=[O:17])=[O:16])=[CH:8][N:9]2[CH3:12])=[CH:4][CH:3]=1

Participants

3

Reactant 2

HCID 24638Chlorosulfonic acidHCID 11074270HCID 11074270, compound

Product 1

HCID 15269533HCID 15269533, compound

Procedure

7-Chloro-1-methyl-4-quinolone (6.9 g) and chlorosulphonic acid (14 ml) were stirred and heated at 140° for 2 hours. The reaction mixture was cooled to room temperature and carefully added dropwise to ice water (200 ml). The solid which formed was collected, washed with water and dried in air to give the novel compound 7-chloro-1-methyl-4-oxo-1,4-dihydroquinoline-3-sulphonyl chloride, m.p. >300°.

Workup

  1. temperatureheated at 140° for 2 hours
  2. customThe solid which formed
  3. customwas collected
  4. washwashed with water
  5. customdried in air

Sources & evidence

ORD record
ord-aac7856c234341d49e8b0701e3b18d12
Source dataset
uspto-grants-1988_09
Patent number
US04772614

Reaction notes

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