Dimethylamine → HCID 21291486, compound

HRID 622689Notes

Reaction equation

HRID 622689 reaction equation
[Cl:1][C:2]1[CH:11]=[C:10]2[C:5]([C:6](=[O:17])[C:7]([S:13](Cl)(=[O:15])=[O:14])=[CH:8][N:9]2[CH3:12])=[CH:4][CH:3]=1.[CH3:18][NH:19][CH3:20]>>[Cl:1][C:2]1[CH:11]=[C:10]2[C:5]([C:6](=[O:17])[C:7]([S:13]([N:19]([CH3:20])[CH3:18])(=[O:15])=[O:14])=[CH:8][N:9]2[CH3:12])=[CH:4][CH:3]=1

Participants

3

Reactant 2

HCID 674DimethylamineHCID 15269533HCID 15269533, compound

Product 1

HCID 21291486HCID 21291486, compound

Procedure

A mixture of 7-chloro-1-methyl-4-oxo-1,4-dihydroquinoline-3-sulphonyl chloride (7.3 g) and dimethylamine (33% w/w solution in industrial methylated spirit; 150 ml) was stirred at room temperature for 72 hours. The precipitate and residue from evaporation of the filtrate were combined and crystallised from industrial methylated spirit. The product was ground under water, collected and dried to give the novel compound 7-chloro-1,N,N-trimethyl-4-oxo-1,4-dihydroquinoline-3-sulphonamide, m.p. 207°-209°.

Workup

  1. customThe precipitate and residue from evaporation of the filtrate
  2. customcrystallised from industrial methylated spirit
  3. customcollected
  4. customdried

Sources & evidence

ORD record
ord-8f2054e748a24da0bf04db3d2f0ea670
Source dataset
uspto-grants-1988_09
Patent number
US04772614

Reaction notes

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