Benzylamine → HCID 21291503, compound

HRID 622691Notes

Reaction equation

HRID 622691 reaction equation
[Cl:1][C:2]1[CH:11]=[C:10]2[C:5]([C:6](=[O:17])[C:7]([S:13](Cl)(=[O:15])=[O:14])=[CH:8][N:9]2[CH3:12])=[CH:4][CH:3]=1.[CH2:18]([NH2:25])[C:19]1[CH:24]=[CH:23][CH:22]=[CH:21][CH:20]=1>>[CH2:18]([NH:25][S:13]([C:7]1[C:6](=[O:17])[C:5]2[C:10](=[CH:11][C:2]([Cl:1])=[CH:3][CH:4]=2)[N:9]([CH3:12])[CH:8]=1)(=[O:15])=[O:14])[C:19]1[CH:24]=[CH:23][CH:22]=[CH:21][CH:20]=1

Participants

3

Reactant 2

HCID 7504BenzylamineHCID 15269533HCID 15269533, compound

Product 1

HCID 21291503HCID 21291503, compound

Procedure

7-Chloro-1-methyl-4-oxo-1,4-dihydroquinoline-3-sulphonyl chloride (9.2 g) was added portionwise to a stirred solution of benzylamine (10.5 ml) in absolute alcohol (300 ml). The mixture was stirred at ambient temperature for 24 hours, then evaporated to dryness. The residue was crystallised from industrial methylated spirit to give the novel compound N-benzyl-7-chloro-1-methyl-4-oxo-1,4-dihydroquinoline-3-sulphonamide, m.p. 208°-210°.

Workup

  1. customevaporated to dryness
  2. customThe residue was crystallised from industrial methylated spirit

Sources & evidence

ORD record
ord-2c939f6119ad4b0794df0c081e6ae527
Source dataset
uspto-grants-1988_09
Patent number
US04772614

Reaction notes

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