HuagongsheHuagongshe Chemistry Print Report · For research reference only
N,N-Dimethylmethanesulphonamide → 1-(2-amino-4-chloro-5-methoxyphenyl)-2-(N,N-dimethylsulphamoyl)ethanone
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | N,N-Dimethylmethanesulphonamide | HCID 70191 | — |
| Reactant | Ethyl 2-amino-4-chloro-5-methoxybenzoate | HCID 21291464 | — |
| Reactant | Butyllithium | HCID 178418339 | — |
| Product | 1-(2-amino-4-chloro-5-methoxyphenyl)-2-(N,N-dimethylsulphamoyl)ethanone | HCID 21291495 | — |
Reaction Steps
In a similar manner to tht described in Example 12(a), N,N-dimethylmethanesulphonamide was reacted with n-butyl lithium and the product reacted with ethyl 2-amino-4-chloro-5-methoxybenzoate to give the novel compound 1-(2-amino-4-chloro-5-methoxyphenyl)-2-(N,N-dimethylsulphamoyl)ethanone, m.p. 59°-62°.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04772614 |
| Source dataset | uspto-grants-1988_09 |
| ORD ID | ord-d5e783f4a51a4bd9b76015ea68f29918 |
| Source note | uspto-grants-1988_09 |