Sodium Hydroxide → HCID 15034333, compound

HRID 622737Notes

Reaction equation

HRID 622737 reaction equation
Cl.[CH2:2]([NH:9][CH2:10][CH2:11][O:12][C:13]1[CH:18]=[CH:17][C:16]([OH:19])=[CH:15][CH:14]=1)[C:3]1[CH:8]=[CH:7][CH:6]=[CH:5][CH:4]=1.[OH-].[Na+]>ClCCl>[CH2:2]([NH:9][CH2:10][CH2:11][O:12][C:13]1[CH:14]=[CH:15][C:16]([OH:19])=[CH:17][CH:18]=1)[C:3]1[CH:4]=[CH:5][CH:6]=[CH:7][CH:8]=1

Participants

4

Reactant 2

HCID 14798Sodium HydroxideHCID 22154105HCID 22154105, compound

Product 1

HCID 15034333HCID 15034333, compound

Reagents, catalysts & solvents 1

HCID 6344DichloromethaneSolvent

Procedure

N-Benzyl-2-p-hydroxyphenoxyethylamine hydrochloride (3.5 g) was shaken with 1M sodium hydroxide solution (20 ml) and dichloromethane (20 ml). The organic layer was separated and washed with water (10 ml), dried (MgSO4) and the solvent evaporated to give N-benzyl-2-p-hydroxyphenoxyethylamine as an oil.

Workup

  1. customThe organic layer was separated
  2. washwashed with water (10 ml)
  3. dry with materialdried (MgSO4)
  4. customthe solvent evaporated

Sources & evidence

ORD record
ord-24d16cbddfa34dff8f16681f9d1ad108
Source dataset
uspto-grants-1988_09
Patent number
US04772631

Reaction notes

Loading…