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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 622752Generated: October 25, 2026

L-Proline → 7-methyl-3,4-dihydro-4-methyl-2H-1,4-benzodiazepine-2,5(1H)-dione

https://huagongshe.com/reaction/622752

Reaction equation

Participants

RoleNameHCIDCharge
ReactantL-ProlineHCID 145742—
Reactant(S)-7-methyl-1,2,3,11a-tetrahydro-5H-pyrrolo(2,1-c)(1,4)benzodiazepine-5,11(10H)-dioneHCID 10198508—
Product7-methyl-3,4-dihydro-4-methyl-2H-1,4-benzodiazepine-2,5(1H)-dioneHCID 21291978—

Reaction Steps

(S)-7-methyl-1,2,3,11a-tetrahydro-5H-pyrrolo(2,1-c)(1,4)benzodiazepine-5,11(10H)-dione by reaction with L-proline. M.p. 243.1-244.5° C.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS04772696
Source datasetuspto-grants-1988_09
ORD IDord-8587f2f2d9f044fb97992d7f34e07480
Source noteuspto-grants-1988_09