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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 622841Generated: October 25, 2026

Propargyl alcohol → 1-(3-Bromo-1,2-oxazol-5-yl)ethan-1-ol

https://huagongshe.com/reaction/622841

Reaction equation

Participants

RoleNameHCIDCharge
ReactantPropargyl alcoholHCID 7859—
ReactantPhenylacetyleneHCID 10821—
ReactantEthyl propiolateHCID 12182—
Reactant3-Butyn-1-OLHCID 13566—
Reactant3-Butyn-2-olHCID 16239—
ReactantCarbonimidic dichloride, hydroxy-HCID 65582—
Reactant1-Pentyn-3-olHCID 92981—
Reactant1-bromo-N-hydroxymethanecarbonimidoyl bromideHCID 2763219—
ReactantHex-1-yn-1-olHCID 15256937—
Product1-(3-Bromo-1,2-oxazol-5-yl)ethan-1-olHCID 13802086—

Reaction Steps

In a similar manner dibromoformaldoxime is reacted with propargyl alcohol, ethyl propiolate, phenylacetylene, 1-pentyn-3-ol, 1-hexyn-1-ol, 3-butyn-1-ol, n-butyl 2-hydroxy-3-butanoate, and dichloroformaldoxime is reacted with 3-butyn-2-ol and propargyl alcohol, to afford the following compounds respectively:

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS04772719
Source datasetuspto-grants-1988_09
ORD IDord-e2790176ba284dc9af7192c6e5b3f99c
Source noteuspto-grants-1988_09