HuagongsheHuagongshe Chemistry Print Report · For research reference only
Dabco → HCID 13366176, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Dabco | HCID 9237 | — |
| Reactant | 2-Amino-4,6-dimethoxypyrimidine | HCID 118946 | — |
| Reactant | Methyl 5-{2-[(oxomethylidene)sulfamoyl]phenyl}furan-2-carboxylate | HCID 13630968 | — |
| Solvent | Acetonitrile | HCID 6342 | — |
| Product | HCID 13366176 | HCID 13366176 | 93.2% |
Reaction Steps
Under a nitrogen atmosphere, a mixture of 2.5 g of the product of Example 3, 0.9 g of 2-amino-4,6-dimethoxypyrimidine, and a few crystals of DABCO in 15 ml of dry acetonitrile was heated at 50°-55° for 1 hour, then stirred at 25° overnight. The solid was filtered off, washed with acetonitrile and 1-chlorobutane, and dried at 60° in vacuo to give 2.5 g of the title compound, mp=215°-217°(d).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04773927 |
| Source dataset | uspto-grants-1988_09 |
| ORD ID | ord-99f29834e2904569916440ec568ffc57 |
| Source note | uspto-grants-1988_09 |