HuagongsheHuagongshe Chemistry Print Report · For research reference only
Ethylene Glycol → 1-Methylindole
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Ethylene Glycol | HCID 174 | — |
| Reactant | N-Methylaniline | HCID 7515 | — |
| Catalyst | Ruthenium | HCID 23950 | — |
| Product | 1-Methylindole | HCID 11781 | 51% |
Reaction Steps
In Tetrahedron Letters, Vol. 27, No. 3, pp. 377-380, 1986, Watanabe discloses the reaction of N-methylaniline with ethylene glycol in the presence of a homogeneous ruthenium catalyst to provide a 51% yield of 1-methylindole. He also reported that: ##STR4##
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04774336 |
| Source dataset | uspto-grants-1988_09 |
| ORD ID | ord-50c3f3df2a0e417fb594119b9c8f892a |
| Source note | uspto-grants-1988_09 |