HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 623279Generated: October 29, 2026
N,N-Diethylethylenediamine → N-diethylaminoethyl-2-amino-3-methyl-5-bromobenzamide
https://huagongshe.com/reaction/623279
Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | N,N-Diethylethylenediamine | HCID 60993 | — |
| Reactant | Methyl 2-amino-5-bromo-3-methylbenzoate | HCID 2763413 | — |
| Solvent | Ethanol | HCID 702 | — |
| Product | N-diethylaminoethyl-2-amino-3-methyl-5-bromobenzamide | HCID 118496629 | 84.2% |
Reaction Steps
To a 100 mL round-bottom flask, 0.1 mol of 2-amino-3-methyl 5-bromobenzoic acid methyl ester having the structural formula of VIII-2, 100 mL of ethanol, 0.3 mol of N,N-diethyl ethylenediamine were added, heated to 78° C. and reacted for 4 hours, after treatment 27.5 grams of N-diethylaminoethyl-2-amino-3-methyl-5-bromobenzamide having a structural formula of III-2 was obtained, and the yield was 84.2%;
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
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| Patent number | US09301529B2 |
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| Source dataset | uspto-grants-2016_04 |
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| ORD ID | ord-e4ad890d40d44f70a28960b2754401a0 |
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| Source note | uspto-grants-2016_04 |
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