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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 623381Generated: October 26, 2026

(1R,3S)-methyl 3-aminocyclopentanecarboxylate → (1R,3S)-Methyl 3-(2',4'-difluorobiphenyl-4-ylsulfonamido)cyclopentanecarboxylate

https://huagongshe.com/reaction/623381

Reaction equation

Participants

RoleNameHCIDCharge
Reactant(1R,3S)-methyl 3-aminocyclopentanecarboxylateHCID 10464431—
Reactant2',4'-Difluoro-biphenyl-4-sulfonyl chlorideHCID 44891094—
Product(1R,3S)-Methyl 3-(2',4'-difluorobiphenyl-4-ylsulfonamido)cyclopentanecarboxylateHCID 68300393—

Reaction Steps

Using a method analogous to Method A, using (1R,3S)-methyl 3-aminocyclopentanecarboxylate and 2′,4′-difluorobiphenyl-4-sulphonyl chloride, the title compound was obtained as a pale yellow gum.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS09302984B2
Source datasetuspto-grants-2016_04
ORD IDord-e73ebdab53a843a9b4badb17a3c8f8fc
Source noteuspto-grants-2016_04