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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 623439Generated: October 27, 2026

1-(3-(Trifluoromethoxy)phenyl)ethanone → (R)-2-methyl-N-(1-(3-(trifluoromethoxy)phenyl)ethyl)propane-2-sulfinamide

https://huagongshe.com/reaction/623439

Reaction equation

Participants

RoleNameHCIDCharge
Reactant1-(3-(Trifluoromethoxy)phenyl)ethanoneHCID 737161—
Reactanttert-Butylsulfinamide, (R)-(+)-HCID 10964479—
Product(R)-2-methyl-N-(1-(3-(trifluoromethoxy)phenyl)ethyl)propane-2-sulfinamideHCID 6751163583%

Reaction Steps

The title compound is prepared in 83% yield (0.38 g, a white solid) from 1-(3-(trifluoromethoxy)phenyl)ethanone (0.30 g, 1.47 mmol) and (R)-2-methylpropane-2-sulfinamide by the similar manner in Step-4 of Amine-1.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS09302991B2
Source datasetuspto-grants-2016_04
ORD IDord-6a79089be5224c26b1c233930fb0814b
Source noteuspto-grants-2016_04