HuagongsheHuagongshe Chemistry Print Report · For research reference only
Cyclopropanecarboxamide → Methyl 2-(cyclopropanecarboxamido)pyrimidine-4-carboxylate
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Cyclopropanecarboxamide | HCID 80376 | — |
| Reactant | Methyl 2-chloropyrimidine-4-carboxylate | HCID 43811076 | — |
| Product | Methyl 2-(cyclopropanecarboxamido)pyrimidine-4-carboxylate | HCID 67509747 | — |
Reaction Steps
The title compound is prepared in quantitative yield (1.93 g, a pale yellow solid) from methyl 2-chloropyrimidine-4-carboxylate (1.50 g, 8.69 mmol) and cyclopropanecarboxamide by the similar manner in Step-1 of Carboxylic acid-4.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09302991B2 |
| Source dataset | uspto-grants-2016_04 |
| ORD ID | ord-cd0932d17f7c4830b2c7075b30648345 |
| Source note | uspto-grants-2016_04 |