Propionamide → HCID 67509707, compound

HRID 623561Notes

Reaction equation

HRID 623561 reaction equation
Cl[C:2]1[CH:3]=[C:4]([CH:9]=[C:10]([CH3:12])[N:11]=1)[C:5]([O:7][CH3:8])=[O:6].[C:13]([NH2:17])(=[O:16])[CH2:14][CH3:15]>>[CH3:12][C:10]1[CH:9]=[C:4]([CH:3]=[C:2]([NH:17][C:13](=[O:16])[CH2:14][CH3:15])[N:11]=1)[C:5]([O:7][CH3:8])=[O:6]

Participants

3

Reactant 2

HCID 6578PropionamideHCID 2759833Methyl 2-Chloro-6-methylisonicotinate

Product 1

HCID 67509707HCID 67509707, compoundYield 60%

Procedure

The title compound is prepared in 60% yield (2.16 g, a pale yellow solid) from methyl 2-chloro-6-methylisonicotinate (3.00 g, 16.2 mmol) and propionamide by the similar manner in Step-1 of Carboxylic acid-4.

Sources & evidence

ORD record
ord-98cb7c4954984709af93162ae072cf51
Source dataset
uspto-grants-2016_04
Patent number
US09302991B2

Reaction notes

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