HuagongsheHuagongshe Chemistry Print Report · For research reference only
Methyl 2-chloropyridine-4-carboxylate → Methyl 2-(1-methylcyclopropanecarboxamido)isonicotinate
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Methyl 2-chloropyridine-4-carboxylate | HCID 2736842 | — |
| Reactant | 1-Methylcyclopropanecarboxamide | HCID 13002936 | — |
| Product | Methyl 2-(1-methylcyclopropanecarboxamido)isonicotinate | HCID 67510645 | 86% |
Reaction Steps
The title compound is prepared in 86% yield (0.30 g, a white solid) from methyl 2-chloroisonicotinate (0.25 g, 1.46 mmol) and 1-methylcyclopropanecarboxamide by the similar manner in Step-1 of Carboxylic acid-4.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09302991B2 |
| Source dataset | uspto-grants-2016_04 |
| ORD ID | ord-651c8977760c49339621136fffc3dbac |
| Source note | uspto-grants-2016_04 |