HuagongsheHuagongshe Chemistry Print Report · For research reference only
HCID 20261895, compound → HCID 67511217, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | HCID 20261895 | HCID 20261895 | — |
| Reactant | 1-[6-(2,2,2-Trifluoroethoxy)-pyridin-3-yl]-ethylamine hydrochloride | HCID 67509413 | — |
| Product | HCID 67511217 | HCID 67511217 | 39% |
Reaction Steps
The title compound is prepared in 39% yield (213 mg, a white solid) from (−)-1-(6-(2,2,2-trifluoroethoxy)pyridin-3-yl)ethanamine hydrochloride (379 mg, 1.48 mmol, Amine-1, single enantiomer) and 2-amino-5-chloroisonicotinic acid (280 mg, 1.62 mmol) by the similar manner in Step-1 of Example-8.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09302991B2 |
| Source dataset | uspto-grants-2016_04 |
| ORD ID | ord-eb66872b7d274cc1b00c03ffbbbdccfa |
| Source note | uspto-grants-2016_04 |