HuagongsheHuagongshe Chemistry Print Report · For research reference only
Propionyl chloride → HCID 67509729, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Propionyl chloride | HCID 62324 | — |
| Reactant | HCID 67511217 | HCID 67511217 | — |
| Product | HCID 67509729 | HCID 67509729 | 44% |
Reaction Steps
The title compound is prepared in 44% yield (10 mg) from 2-amino-5-chloro-N-(1-(6-(2,2,2-trifluoroethoxy)pyridin-3-yl)ethyl)isonicotinamide (20 mg, 0.053 mmol, single enantiomer, Step-1) and propionyl chloride (6 mg, 0.080 mmol) by the similar manner in Step-2 of Example-8.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09302991B2 |
| Source dataset | uspto-grants-2016_04 |
| ORD ID | ord-32eeacd4ef684d92b30fdb10bc055fd5 |
| Source note | uspto-grants-2016_04 |